Plasma levels of sRAGE, loss of aeration and weaning failure in ICU patients: a prospective observational multicenter study.
Postextubation distress after a successful spontaneous breathing trial (SBT) is associated with increased morbidity and mortality.Lung ultrasound determination of changes in lung aeration predicts weaning failure.It remains unknown whether this derecruitment is related to alveolar epithelial dysfunction or not.To verify whether lung alveolar type I